What is one of the primary effects of calcium channel blockers?

What is one of the primary effects of calcium channel blockers?

• A. Increases heart rate
• B. Reduces myocardial oxygen demand
• C. Increases blood viscosity
• D. Decreases renal blood flow

Answer: (B)

The primary effect of calcium channel blockers is that they reduce myocardial oxygen demand. These medications work by blocking calcium from entering the cells of the heart and blood vessel walls. When calcium influx is inhibited, the heart's contractility decreases, leading to a reduction in the force of contraction. Additionally, calcium channel blockers cause vasodilation, which reduces the workload on the heart and the amount of oxygen it requires. This is particularly beneficial for patients with conditions like angina, where lowering the oxygen demand of the heart can relieve chest pain and improve exercise tolerance. Understanding this mechanism is essential, as it directly ties into the clinical use of calcium channel blockers in managing hypertension and various cardiac conditions. In contrast, the options related to increasing heart rate, increasing blood viscosity, and decreasing renal blood flow do not reflect the primary action of this class of medications, which focuses on reducing cardiac workload and improving blood flow.

The primary effect of calcium channel blockers is that they reduce myocardial oxygen demand. These medications work by blocking calcium from entering the cells of the heart and blood vessel walls. When calcium influx is inhibited, the heart's contractility decreases, leading to a reduction in the force of contraction. Additionally, calcium channel blockers cause vasodilation, which reduces the workload on the heart and the amount of oxygen it requires. This is particularly beneficial for patients with conditions like angina, where lowering the oxygen demand of the heart can relieve chest pain and improve exercise tolerance.

Understanding this mechanism is essential, as it directly ties into the clinical use of calcium channel blockers in managing hypertension and various cardiac conditions. In contrast, the options related to increasing heart rate, increasing blood viscosity, and decreasing renal blood flow do not reflect the primary action of this class of medications, which focuses on reducing cardiac workload and improving blood flow.